Vegan Hyaluronic Acid - made using genetically manipulated Bacillus

18 April 2018

If you believed all the hype on the internet, you’d think Hyaluronic Acid was a miracle moisturiser.d.

In reality, the opposite is true – and to a startling degree.

That’s why you’ll never find Hyaluronic Acid in a Simplicité product, not even the so-called vegan version.

Founder David Lyons sees beyond the hype because more than 30 years of clinical experience tells him Hyaluronic Acid will not give lasting results. And here’s why:

How Hyaluronic Acid is made

Vegan Hyaluronic Acid is often used in organic and natural skin care ranges, so you would expect that it is made entirely from plants. You might even hear that it is extracted from wheat through a fermentation process. Sounds wholesome enough.

But the truth is, one 'vegan' version of Hyaluronic Acid uses Bacillus subtilis (a bacteria that is found in soil and the gut of humans and some types of animals) which has been modified, mainly in Chinese factories, by deleting certain genes,  inserting a gene from Streptococcus equisimilus and then cloning.1.

Another 'vegan' Hyaluronic Acid is made, again mainly in Chinese factories, through the fermentation of Streptococcus zooepidemicus, a bacteria commonly found in the bowels and lungs of horses with influenza.2. 

Whether 'vegan' HA is made from the former or latter version above, our point is that it still will not of any help to skin. 

Apart from that, surely no self-respecting vegan would use this stuff if they knew its origins.


Hyaluronic acid is made by fermentation of Streptococcus zooepidemicus - horse flu virus
                    One version of HA is made from
Streptococcus zooepidemicus (horse flu) bacteria. 

It’s not much better than non-vegan Hyaluronic Acid, which is made from rooster combs, eyeballs and giblets. Doesn’t bear thinking about, really.

Hyaluronic Acid is is made from boiled up roosters' combs or other animal tissue
Non-vegan Hyaluronic Acid is made from rooster combs 
and other animal tissue.

Why Hyaluronic Acid doesn’t deliver

As a naturally occurring molecule in our epidermis, Hyaluronic Acid is a marvellous thing. It can hold up to 1000 times its weight in water, promote collagen production and give skin that delightful plumpness we all associate with youth.

But, sadly, once naturally occurring HA is lost through ageing, it is gone for ever.

Whatever its source, Hyaluronic Acid can't help 

Using products that contain Hyaluronic Acid, no matter how this is sourced, in the hope it will draw moisture to the skin, or replenish our natural stores, is wishful thinking. This applies just as much to Hyaluronic Acid supplements as to Hyaluronic Acid skin care.

In fact, due to the very large size of its molecules 5., Hyaluronic Acid has a hard time penetrating the epidermis. Users of Hyaluronic Acid skin care products frequently complain of the product “pilling” on their skin, which is all the evidence you need that it is not being absorbed.

So, the irony is that, as it sits on the surface of the skin, Hyaluronic Acid – with its great affinity for water – actually draws moisture out of the epidermis where it is most needed.

Hyaluronic Acid will deplete your skin 

Yes, despite claims to the contrary, Hyaluronic Acid will actually dehydrate your skin over time.

Not only that, but Hyaluronic Acid has been shown to promote the build-up of keratin cells. These are the cells responsible for the flakiness you see on sun-damaged skin. So even if you think you see some improvement initially, it will soon be all downhill from there.

So, what’s the alternative?  

Certain eye disorders and joint problems can show significant improvement with forms of Hyaluronic Acid.

 In the world of skin care, our hope is that those who choose to use the various forms of hyaluronates, back up their skin care regime with plant sourced nutrients. It's our choice to avoid them.

At Simplicité, when we say our products are ‘natural’, we mean handcrafted from plant extracts that are easily absorbed, high in quality, and in concentrations designed to resist the damaging effects of sun and ageing.

We don’t use dubious powders from China. We don’t bulk up our products with unnecessary fillers or disguise natural aromas with fragrance. We certainly would never use cheap ingredients, such as Hyaluronic Acid, that promise results but don’t deliver.

Instead, we are meticulous in creating the concentrated, medicinal-grade plant extracts that go into our certified organic products.

We are a cruelty-free and vegan brand accredited by both PETA Beauty without Bunnies and Choose Cruelty Free.

And most importantly, for 25 years now, our products have given consistently stunning results for perfectly hydrated skin.

Avoid Hyaluronic Acid if you want great skin

If it is younger-looking skin you seek, forget about Hyaluronic Acid.

The best way to try natural and organic skin care that gives results and is made from effective, non-pathogenic ingredients is to start with our Basic Six Trial Pack. Take this simple Skin Test to determine which pack to choose.

Our Results Lift Gel is a lightweight, natural vitamin C formula that helps to hydrate and refresh dull, tired skin.

Simplicité Face Oils are also especially formulated for deep rehydration and will leave your skin feeling soft and supple, never oily. Apply as a nourishing primer before makeup and under your moisturiser before you go to bed at night.

You’ll sleep easier, knowing you’re properly hydrating your skin with products that aren’t made from a horse flu pathogen.

There isn't a 'plant based' Hyaluronic Acid

Please note: Hyaluronic Acid/Sodium Hyaluronate exists ONLY in the tissues of mammals, or the exterior wall of Streptococcal bacteria.

Polysaccharides from the Cassia/Senna plant are not Hyaluronic Acid/Sodium Hyaluronate. These polysaccharides are merely claimed to ‘mimic’ the action of HA.

The Cassia/Senna plant has a long history as being used as a laxative. It’s also a known sensitiser to human skin.

Alleged ‘proven science’ about Senna polysaccharides on manufacturer’s websites is nothing more than a simple self-run test. These tests are not properly controlled, independent studies. They are not published on any recognised reference websites such as NCBI.

What are your experiences with Hyaluronic Acid?

Please leave your comments below.


1. Vegan Hyaluronic Acid made using genetically manipulated Bacillus

2. Vegan Hyaluronic Acid is produced from a pathogenic substance.

3. 13-Aug-2010 - Novozymes Biopharma attempted to produce vegan Hyaluronic Acid using a non-pathogenic method by fermentation of production strain, Bacillus subtilis.

4. 14-Jan-2008 - Novozymes closes Hyaluronic Acid manufacturing plant because the above attempt to produce using a non-pathogenic method failed commercially.

5. Skin can't absorb Hyaluronic Acid because of its very large molecular weight.

Comments (11)

Simplicite Skin on November 30, 2018

Replying to Jamie, below, who asked: Is it 100% accurate that vegan HA comes from horses?"

Yes Jamie, our information in the article is accurate about the source of Ha.

Jamie on November 30, 2018

I was under the impression that botanical hyaluronic acid is derived from a yellow flower called cassia angustifolia native to Eygpt. Is it 100% accurate that vegan HA comes from horses?

Simplicite Skin on July 02, 2018

Replying to Desiree who asked: HA has damaged the skin around my eyes. Do you have a eye product? I need to find something to super moisturize this area.
Hi Desiree
The darkness under the eyes is likely due to your over-response/sensitivity to the HA (Hyaluronic Acid/Sodium Hyaluronate). The effect of HA in the thin skin under the eyes may, in some people, even at low doses, produce loosening of the cellular bonds in the tissues.
Non-animal HA and its salts are produced from Streptococcus fermentation . There is ’growing concern due to the fact that streptococci are pathogenic. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239841/#!po=75.0000

What to do? How to restore firmness and elasticity? Use our Instant Help Eye Gel three times daily, apply very thinly. And apply our Firming Rehydration Eye Creme three times daily as well, over the top of the Instant Help Eye Gel.
Both of these products contain important ACTIVES…compounds found in medicinal quality citrus extracts (and other plants), inhibit the breaking down of collagen and elastin in the skin. Pharmacognosy Res. 2016 PMCID: PMC4908842 Evaluation of Skin Anti-aging Potential of Citrus reticulata Blanco Peel

Compounds found in the essential oils of Lemon, Orange, Lime, Mandarin, and Rose Geranium, have been shown to display remarkable rejuvenating properties for the skin. A study showed a significant decrease in the number and length of wrinkles around the eyes. 84% of the subjects considered that the treatment had a positive effect on fine wrinkles. The size of open pores was also significantly reduced.
Anti-inflammatory and skin repair treatments with d-limonene

Published evidence says compounds found in the essential oils of Rose Geranium, Cinnamon, Vietnamese Rosewood, Birch leaf (OneStep Exfoliating Cleanser) is an active antioxidant (slows ageing), it’s also anti-inflammatory, and for those with sensitive skin it relieves pain.
Linalool in Essential Plant Oils: Pharmacological Effects Chapter DOI: 10.13140/2.1.1015.2963
It’s important to act early and apply the products frequently to get the best restoration results.

Simplicite on June 21, 2018

Heather – yes, our sources for the information about Hyaluronic Acid and its manufacture etc are credible and are hyperlinked throughout the article. They are also listed below it.

heather on June 16, 2018

Do you have any sources for your information? I’d like to quote your article but I need to know this information is from a credible source, thanks

Desiree on July 02, 2018

HA has damaged the skin around my eyes. Do you have a eye product? I need to find something to super moisturize this area.

Simplicite Skin Care on May 09, 2018

LESLI – to answer your question,’What about supplementing internally??
A. Using products that contain Hyaluronic Acid in the hope it will draw moisture to the skin, or replenish our natural stores, is wishful thinking.
This applies just as much to Hyaluronic Acid supplements as to Hyaluronic Acid skin care.

Lesli on May 09, 2018

What about supplementing internally??

char on April 19, 2018

I’ve tried using HA skincare proucts on and for the past 3 years and every time within 3-4 days my skin sags and the wrinkles get worse! It damaged the structure of my skin on a cellular level. I tried these HA products to improve the appearance of my hooded eyes which appeared to improve it initially. Only to have the effects wear off after using the product 3 days. I woke up in the morning after using the H A products only to find my hooded eyes had become worse. The skin had lost the firmness that I originally had prior to using the h a product leaving the skin sagging over my eyelashes. Hyaluronic acid is very dangerous and should not be used in any topical or injectable product. I’ve also read in some research reports that HA accelerates the growth of cancer cells as well as causes ischemia to dermis tissue tissue. With so many products on the market containing ha currently it’s become difficult to find products that don’t contain it. I live in the u.s. if anybody knows where I can find good anti age products here in the US that don’t contain hyaluronic acid please let me know. Thank you!

Kim London on April 19, 2018

Wow – thank you for explaining the origins of this nasty ingredient. I am vegetarian and had absolutely no idea how hyaluronic acid was made. Safe to say I will not be using any products that include this and will be steering clear of any salons or spas that also use products that feature this. When is Simplicite going to open their own say spa? ; )

Annalies Nutley on April 19, 2018

I’ve used so many products in the past that contained hyaluronic acid yet it never gave the results it promised. After reading this I am definitely shocked at the truth behind this fake miracle for the skin. Thank you for revealing how this crap is made…I’ve shared this on my FB page for others who probably don’t know anything about this!

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